Jinan Shenghe Chemical Co., Ltd. (+-)-PGF2-alpha

(+-)-PGF2-alpha

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CAS: 23518-25-4 Non-hazardous / General Chemical

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Detailed Chemical Properties & Synonyms

Synonyms dinoprostprostaglandin F2alphaPGF2alphaProstaglandin F2aamoglandinEnzaprostpanacelanDinoprostaProtamodinProstaglandin F2-alphal-PGF2-alphaPGF2a

Description

(+-)-PGF2-alpha · CAS 23518-25-4 · C20H34O5. UNII B7IN85G1HY. Melting Point: 25-35 °C; LogP: 2.72; Collision Cross Section: 194.1 Å² [M-H]-.

Identification

CAS Registry Number	23518-25-4
PubChem CID	5280363
Molecular formula	C20H34O5
IUPAC name	(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid
UNII (FDA)	B7IN85G1HY

Computed Descriptors

Molecular Weight	354.5
XLogP3	2.7
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	12
Exact Mass	354.24062418
Monoisotopic Mass	354.24062418
Topological Polar Surface Area	98
Heavy Atom Count	25
Formal Charge	0

Physical & Chemical Properties

Melting Point	25-35 °C
LogP	2.72
Collision Cross Section	194.1 Å² [M-H]-
Collision Cross Section	204.4 Å² [M+Na]+

Physical description & handling notes

NATURAL FORM, CRYSTALS
SOL IN WATER 200 MG/ML /DINOPROST TROMETHAMINE/
FREELY SOL IN METHANOL, ABSOLUTE ETHANOL; FREELY SOL IN ETHYL ACETATE, CHLOROFORM; SLIGHTLY SOL IN WATER
STABLE FOR 2 YR IN LIGHT RESISTANT CONTAINERS @ 5-15 °C
DEGRADES IN 1 WK WHEN EXPOSED TO SUNLIGHT OR IN 3 MO @ 40 °C
STABLE IN LIGHT, AIR, & HEAT /DINOPROST TROMETHAMINE/

GHS Hazard Classification

Reported hazard statements	H302 (100%), H319 (89.7%), H360 (97.4%), H370 (89.7%), H372 (89.7%)

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H319 (89.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Documented Uses

…SYNTH OF NATURAL PROSTAGLANDIN F2ALPHA: SCHNEIDER, MURRAY, J ORG CHEM 38, 397 (1973).
…20-CARBON UNSATURATED CARBOXYLIC ACIDS WITH CYCLOPENTANE RING. …KINSHIP WITH ESSENTIAL FATTY ACIDS… MAIN CLASSES–E, F, A, B, C, & D-DISTINGUISHED BY CONSTITUENTS OF…RING. …SUBDIVIDED…WITH NUMBER OF DOUBLE BONDS IN SIDE CHAINS. …INDICATED BY SUBSCRIPT…REFLECTS FATTY ACID PRECURSOR. /PROSTAGLANDINS/
PROSTAGLANDINS OF E & FALPHA SERIES ARE SOMETIMES REFERRED TO AS "PRIMARY PROSTAGLANDINS". …MOST ABUNDANT (ESP E2 & F2ALPHA)… /PROSTAGLANDINS/
IN VIVO MOST CELLS SEEM CAPABLE OF SYNTHESIZING PROSTAGLANDINS FROM ESSENTIAL FATTY ACID PRECURSORS. …BELIEVED THAT ENDOGENOUS BIOSYNTHESIS, IN ABSENCE OF ADDED PRECURSOR ACID, DEPENDS ON PHOSPHOLIPASE-CATALYZED RELEASE OF PRECURSOR ACID FROM CELLULAR PHOSPHOLIPID STORES. /PROSTAGLANDINS/
SYNTH OF PRIMARY PROSTAGLANDINS…BY COMPLEX OF MICROSOMAL ENZYMES REFERRED TO AS "PROSTAGLANDIN SYNTHETASE." INITIAL EVENTS…RESULT IN OXYGENATION & CYCLIZATION OF UNESTERIFIED PRECURSOR ACID TO FORM CYCLIC PEROXIDE DERIV. …ENDOPEROXIDE IS…REDUCED, YIELDING PGFALPHA COMPD. /PROSTAGLANDINS/
MOST PROLIFIC SOURCE OF NATURAL PROSTAGLANDINS IS MARINE ORGANISM CALLED GORGONIAN SEA WHIP, WHICH OCCURS…IN CORAL REEFS, ESP IN CARIBBEAN AREA. HARVESTING OF THESE HAS MADE PRODN…MUCH LESS EXPENSIVE. INTERMEDIATES & CHEM ANALOGS DERIVED FROM THIS NATURAL SOURCE…SYNTONS. /PROSTAGLANDINS/

Synonyms

dinoprost; prostaglandin F2alpha; PGF2alpha; Prostaglandin F2a; amoglandin; Enzaprost; panacelan; Dinoprosta; Protamodin; Prostaglandin F2-alpha; l-PGF2-alpha; PGF2a; PGF-2alpha; PGF2-alpha; Dinoprostum; Prosmon

Frequently Asked Questions

What are the CAS number and molecular formula of (+-)-PGF2-alpha?

CAS 23518-25-4; molecular formula C20H34O5; molecular weight — g/mol.

What other names is (+-)-PGF2-alpha known by?

dinoprost, prostaglandin F2alpha, PGF2alpha, Prostaglandin F2a, amoglandin, Enzaprost.

Is (+-)-PGF2-alpha classified as hazardous?

Hazard statements reported: H302, H319, H360, H370, H372.

What are the key physical properties of (+-)-PGF2-alpha?

Melting Point: 25-35 °C; LogP: 2.72; Collision Cross Section: 194.1 Å² [M-H]-; Collision Cross Section: 204.4 Å² [M+Na]+.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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Packaging & Shipping

Standard: 25 kg fiber drum / 200 kg steel drum with double PE liner
Small pack: 1 kg / 5 kg aluminum foil bag for lab & sample
Custom: packaging size and labeling per customer requirement
Lead time: in-stock items ship within 3-5 business days
Documents: COA, MSDS / SDS, TDS provided with every shipment
Global: air, sea (FCL / LCL) and express to 80+ countries

Storage & Handling

Store in a cool, dry, well-ventilated place away from heat, direct sunlight and incompatible materials. Keep container tightly closed. Use appropriate personal protective equipment and refer to the SDS for full safety guidance before handling.

Frequently Asked Questions

Can you provide a Certificate of Analysis (COA) and sample?

Yes. A batch-specific COA and free or charged sample are available on request before bulk ordering.

Do you support custom synthesis or specific specifications?

Yes. We offer custom grade, particle size and purity adjustment based on your application and order volume.

What are your minimum order quantities (MOQ)?

MOQ depends on the product; small quantities are supported for R&D and trial runs.

How do you ensure consistent quality?

Every batch is tested in-house and retains full traceability from raw material to finished goods.

Why Choose Jinan Shenghe Chemical

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Serving global B2B buyers across the chemical industry since 2013.

Full Range

Products in Catalog

Broad coverage of fine chemicals, additives and intermediates.

80+

Countries Served

Reliable long-term supply with worldwide logistics.

100%

Batch Tested

COA and traceability for every shipment.

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About Jinan Shenghe Chemical Co., Ltd.

Jinan Shenghe Chemical Co., Ltd.

We are a professional chemical supplier based in Jinan, China. Since 2013, we have been connecting manufacturers and global B2B buyers with reliable sourcing, quality-controlled products and efficient logistics.

Our business covers food & feed additives, fine chemicals, pharmaceutical intermediates, eco-materials, coatings and specialty chemicals — all non-hazardous and compliant with our licensed scope.

Company Name

Jinan Shenghe Chemical Co., Ltd.

Business Type

Manufacturer Representative / Trading Company

Location

Jinan, Shandong, China

Main Products

Fine Chemicals, Additives, Intermediates

Export Markets

Asia, Europe, North & South America, Middle East

Documents Supplied

COA, MSDS / SDS, TDS